SPRO insider transaction filings

Spero Therapeutics, Inc. — 29 most recent Form 4 filings from SEC EDGAR, normalized by FilingPulse. Latest filing: 2026-08-06. Screen SPRO transaction legs live →

FiledFormInsiderReported transactionsSource
2026-08-064Zack Debra — Chief Medical OfficerGrant/award (A): 162,311 @ $0 · Grant/award (A): 324,675 (derivative) @ $0EDGAR
2026-06-254Tregoning Kathleen — DirectorGrant/award (A): 10,000 @ $0 · Grant/award (A): 20,000 (derivative) @ $0EDGAR
2026-06-254Smith Cynthia — DirectorGrant/award (A): 10,000 @ $0 · Grant/award (A): 20,000 (derivative) @ $0EDGAR
2026-06-254Jackson Scott Thomas — DirectorGrant/award (A): 10,000 @ $0 · Grant/award (A): 20,000 (derivative) @ $0EDGAR
2026-06-254VINK PATRICK V.J.J. — DirectorGrant/award (A): 10,000 @ $0 · Grant/award (A): 20,000 (derivative) @ $0EDGAR
2026-06-254Deshpande Milind — DirectorGrant/award (A): 10,000 @ $0 · Grant/award (A): 20,000 (derivative) @ $0EDGAR
2026-06-254Pottage John C Jr — DirectorGrant/award (A): 10,000 @ $0 · Grant/award (A): 20,000 (derivative) @ $0EDGAR
2026-06-254THOMAS FRANK E — DirectorGrant/award (A): 10,000 @ $0 · Grant/award (A): 20,000 (derivative) @ $0EDGAR
2026-05-064Rajavelu Esther — See RemarksSale (S): 25,240 @ $2.51EDGAR
2026-02-094Rajavelu Esther — See RemarksSale (S): 37,101 @ $2.36 · Sale (S): 50,816 @ $2.36EDGAR
2026-02-094Keutzer Timothy — Chief Operating OfficerSale (S): 18,652 @ $2.36EDGAR
2026-02-054Keutzer Timothy — Chief Operating OfficerGrant/award (A): 68,000 @ $0 · Sale (S): 18,891 @ $2.20 · Sale (S): 24,224 @ $2.14 · Sale (S): 3,471 @ $2.24 · Grant/award (A): 137,000 (derivative) @ $0EDGAR
2026-02-044Rajavelu Esther — See RemarksGrant/award (A): 249,000 @ $0 · Sale (S): 18,442 @ $2.20 · Grant/award (A): 498,000 (derivative) @ $0EDGAR
2025-11-124Rajavelu Esther — See RemarksSale (S): 40,270 @ $2.37EDGAR
2025-09-034Mahadevia Ankit — DirectorSale (S): 6,572 @ $1.97EDGAR
2025-09-034Keutzer Timothy — Chief Operating OfficerSale (S): 1,695 @ $1.97EDGAR
2025-06-164Tregoning Kathleen — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-06-164Mahadevia Ankit — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-06-164Smith Cynthia — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-06-164Jackson Scott Thomas — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-06-164VINK PATRICK V.J.J. — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-06-164Deshpande Milind — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-06-164Pottage John C Jr — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-06-164THOMAS FRANK E — DirectorGrant/award (A): 20,000 @ $0EDGAR
2025-05-064Rajavelu Esther — See RemarksGrant/award (A): 185,000 @ $0EDGAR
2025-02-054Keutzer Timothy — Chief Operating OfficerGrant/award (A): 266,139 @ $0 · Sale (S): 3,974 @ $0.78 · Sale (S): 27,643 @ $0.78 · Sale (S): 24,920 @ $0.78EDGAR
2025-02-054Rajavelu Esther — CFO & CBOGrant/award (A): 266,139 @ $0 · Grant/award (A): 100,000 @ $0 · Sale (S): 20,689 @ $0.78EDGAR
2025-02-054Shukla Sath — CEO & PresidentGrant/award (A): 751,407 @ $0 · Sale (S): 6,139 @ $0.78 · Sale (S): 42,786 @ $0.78 · Sale (S): 106,408 @ $0.78EDGAR
2025-02-054Mahadevia Ankit — DirectorSale (S): 13,959 @ $0.78 · Sale (S): 55,260 @ $0.78EDGAR

Recent 8-K events — Spero Therapeutics, Inc.

FiledFormItems reportedSource
2026-08-128-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-07-148-K1.01 — Entry into a Material Definitive Agreement
2.03 — Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant
7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2026-06-258-K5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers
5.03 — Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year
5.07 — Submission of Matters to a Vote of Security Holders
9.01 — Financial Statements and Exhibits
EDGAR
2026-06-228-K7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2026-05-138-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-268-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-01-308-K5.02 — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers
8.01 — Other Events
EDGAR
2025-12-198-K8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2025-11-138-K2.02 — Results of Operations and Financial Condition
7.01 — Regulation FD Disclosure
9.01 — Financial Statements and Exhibits
EDGAR
2025-08-128-K2.02 — Results of Operations and Financial Condition
7.01 — Regulation FD Disclosure
9.01 — Financial Statements and Exhibits
EDGAR
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