UPB insider transaction filings

Upstream Bio, Inc. — 32 most recent Form 4 filings from SEC EDGAR, normalized by FilingPulse. Latest filing: 2026-06-17. Screen UPB transaction legs live →

FiledFormInsiderReported transactionsSource
2026-06-174Houghton Adam — Chief Business OfficerSale (S): 700 @ $6.10EDGAR
2026-06-174Deykin Aaron — Chief Medical OfficerSale (S): 895 @ $6.10EDGAR
2026-06-174Ambrose Allison — General CounselSale (S): 477 @ $6.10EDGAR
2026-06-174Sutherland Everett Rand — Chief Executive Officer, DirectorSale (S): 2,095 @ $6.10EDGAR
2026-06-174GRAY MICHAEL — CFO and COOSale (S): 853 @ $6.10EDGAR
2026-06-114Ruddy Marcella K. — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2026-06-114Fleming Harold Edward — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2026-06-114Chimovits Erez — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2026-06-114Ratcliffe Liam — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2026-06-114Beckman Daniella — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2026-06-114Renaud Ronald C JR — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2026-03-174Deykin Aaron — Chief Medical OfficerSale (S): 894 @ $9.29EDGAR
2026-03-174Ambrose Allison — General CounselSale (S): 475 @ $9.29EDGAR
2026-03-174Houghton Adam — Chief Business OfficerSale (S): 699 @ $9.29EDGAR
2026-03-174Sutherland Everett Rand — Chief Executive Officer, DirectorSale (S): 2,093 @ $9.29EDGAR
2026-03-174GRAY MICHAEL — CFO and COOSale (S): 852 @ $9.29EDGAR
2026-01-064Deykin Aaron — Chief Medical OfficerGrant/award (A): 32,000 @ $0 · Grant/award (A): 96,000 (derivative) @ $0EDGAR
2026-01-064Ambrose Allison — General CounselGrant/award (A): 17,000 @ $0 · Grant/award (A): 51,000 (derivative) @ $0EDGAR
2026-01-064Houghton Adam — Chief Business OfficerGrant/award (A): 25,000 @ $0 · Grant/award (A): 75,000 (derivative) @ $0EDGAR
2026-01-064Sutherland Everett Rand — Chief Executive Officer, DirectorGrant/award (A): 75,000 @ $0 · Grant/award (A): 225,000 (derivative) @ $0EDGAR
2026-01-064GRAY MICHAEL — CFO and COOGrant/award (A): 30,500 @ $0 · Grant/award (A): 91,500 (derivative) @ $0EDGAR
2025-06-124Ruddy Marcella K. — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2025-06-124Fleming Harold Edward — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2025-06-124Chimovits Erez — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2025-06-124Ratcliffe Liam — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2025-06-124Beckman Daniella — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2025-06-124Renaud Ronald C JR — DirectorGrant/award (A): 17,096 (derivative) @ $0EDGAR
2025-02-074Houghton Adam — Chief Business OfficerGrant/award (A): 140,000 (derivative) @ $0EDGAR
2025-02-074Deykin Aaron — Chief Medical OfficerGrant/award (A): 165,000 (derivative) @ $0EDGAR
2025-02-074Ambrose Allison — General CounselGrant/award (A): 25,000 (derivative) @ $0EDGAR
2025-02-074Sutherland Everett Rand — Chief Executive Officer, DirectorGrant/award (A): 500,000 (derivative) @ $0EDGAR
2025-02-074GRAY MICHAEL — CFO and COOGrant/award (A): 195,000 (derivative) @ $0EDGAR

Recent 8-K events — Upstream Bio, Inc.

FiledFormItems reportedSource
2026-08-118-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-06-108-K5.07 — Submission of Matters to a Vote of Security HoldersEDGAR
2026-05-138-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-268-K1.01 — Entry into a Material Definitive Agreement
9.01 — Financial Statements and Exhibits
EDGAR
2026-03-268-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2026-02-118-K2.02 — Results of Operations and Financial Condition
7.01 — Regulation FD Disclosure
9.01 — Financial Statements and Exhibits
EDGAR
2026-02-118-K7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2025-11-058-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
2025-09-028-K7.01 — Regulation FD Disclosure
8.01 — Other Events
9.01 — Financial Statements and Exhibits
EDGAR
2025-08-068-K2.02 — Results of Operations and Financial Condition
9.01 — Financial Statements and Exhibits
EDGAR
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