PERCEPTIVE ADVISORS LLC — SEC Form 4 filings
SEC reporting owner CIK 1224962. 34 Form 4 filings on record with FilingPulse; latest filed 2026-08-27.
Transaction summary — filings shown
Covers all 34 filings on record, filed 2024-01-12 to 2026-08-27. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.
- Open-market purchases (code P, non-derivative): 12 legs across 9 filings — 16,740,388 shares, $106,204,628 total (shares × price as filed).
- Open-market sales (code S, non-derivative): 18 legs across 5 filings — 5,772,984 shares, $9,117,600 total (shares × price as filed).
- Other reported legs (grants, option exercises, tax withholding, gifts, derivative-security transactions, …): 43.
- Largest priced transaction: purchase of 2,481,350 shares @ $12.09 ($29,999,522) in Astria Therapeutics, Inc., filed 2024-02-05.
By issuer — same filings
Open-market purchase/sale legs on non-derivative securities, grouped by issuer. Role is as filed on the newest filing for that issuer. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.
| Issuer | Role (as filed) | Filings | Purchases (P) | Sales (S) | Other legs |
|---|---|---|---|---|---|
| Solid Biosciences Inc. (SLDB) | Director, 10% owner | 6 | 2 legs · 8,410,713 sh · $39,011,243 | — | 4 |
| Astria Therapeutics, Inc. (ATXS) | Director | 1 | 1 leg · 2,481,350 sh · $29,999,522 | — | — |
| Acrivon Therapeutics, Inc. (ACRV) | 10% owner | 3 | 1 leg · 2,353,000 sh · $20,000,500 | 5 legs · 2,256,719 sh · $3,762,865 | — |
| Aldeyra Therapeutics, Inc. (ALDX) | 10% owner | 3 | 5 legs · 682,265 sh · $2,768,372 | 1 leg · 3,400,000 sh · $4,828,000 | — |
| Immatics N.V. (IMTX) | Director | 2 | 1 leg · 863,060 sh · $7,499,991 | — | 1 |
| MeiraGTx Holdings plc (MGTX) | Director, 10% owner | 6 | 1 leg · 1,250,000 sh · $5,000,000 | — | 11 |
| Orchestra BioMed Holdings, Inc. (OBIO) | 10% owner | 1 | 1 leg · 700,000 sh · $1,925,000 | — | 1 |
| Lyra Therapeutics, Inc. (LYRA) | 10% owner | 2 | — | 12 legs · 116,265 sh · $526,734 | — |
| LeonaBio, Inc. (LONA) | Director, 10% owner | 3 | — | — | 11 |
| LianBio (LIAN) | Director, 10% owner | 1 | — | — | 6 |
+5 more issuers among the filings shown — every filing appears in the table below.
Form 4 filings — PERCEPTIVE ADVISORS LLC
| Filed | Form | Issuer | Reported transactions | Source |
|---|---|---|---|---|
| 2026-08-27 | 4 | Immatics N.V. (IMTX) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Purchase (P): 863,060 @ $8.69 | EDGAR |
| 2026-07-22 | 4 | Freenome, Inc. (FRNM) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Grant/award (A): 5,500,000 @ $10 | EDGAR |
| 2026-07-13 | 4 | Kardigan, Inc. (KARD) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, Perceptive Capital Solutions Holdings LP, EDELMAN JOSEPH | Grant/award (A): 20,706 @ $0 | EDGAR |
| 2026-07-10 | 4 | LeonaBio, Inc. (LONA) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Grant/award (A): 28,000 (derivative) @ $0 | EDGAR |
| 2026-07-09 | 4 | LeonaBio, Inc. (LONA) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Grant/award (A): 28,000 (derivative) @ $0 | EDGAR |
| 2026-06-18 | 4 | Immatics N.V. (IMTX) | Grant/award (A): 48,000 (derivative) @ $0 | EDGAR |
| 2026-06-15 | 4 | MeiraGTx Holdings plc (MGTX) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Grant/award (A): 60,000 (derivative) @ $0 | EDGAR |
| 2026-06-11 | 4 | Solid Biosciences Inc. (SLDB) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Grant/award (A): 77,500 (derivative) @ $0 | EDGAR |
| 2026-04-23 | 4 | MeiraGTx Holdings plc (MGTX) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Grant/award (A): 555,555 @ $9 · Grant/award (A): 400,000 (derivative) · Grant/award (A): 300,000 (derivative) · Disposition to issuer (D): 400,000 (derivative) · Disposition to issuer (D): 300,000 (derivative) · Grant/award (A): 400,000 (derivative) · +1 more | EDGAR |
| 2026-03-11 | 4 | Solid Biosciences Inc. (SLDB) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Grant/award (A): 8,912,655 (derivative) @ $5.61 | EDGAR |
| 2026-01-02 | 4 | MeiraGTx Holdings plc (MGTX) jointly with EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Disposition to issuer (D): 2,300,000 @ $7.91 | EDGAR |
| 2025-12-23 | 4 | Athira Pharma, Inc. (ATHA) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH, Perceptive Xontogeny Venture Fund II, LP | Grant/award (A): 989,270 @ $6.35 · Grant/award (A): 329,756 @ $6.35 · Grant/award (A): 1,372,935 (derivative) @ $6.35 · Grant/award (A): 3,838,583 (derivative) @ $6.35 · Grant/award (A): 3,543,307 (derivative) @ $6.35 · Grant/award (A): 457,645 (derivative) @ $6.35 · +3 more | EDGAR |
| 2025-11-13 | 4 | Lyra Therapeutics, Inc. (LYRA) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, Perceptive LS (A), LLC, EDELMAN JOSEPH | Sale (S): 4,783 @ $4.31 · Sale (S): 537 @ $4.31 · Sale (S): 7,862 @ $4.06 · Sale (S): 883 @ $4.06 · Sale (S): 28,597 @ $3.90 · Sale (S): 3,213 @ $3.90 | EDGAR |
| 2025-11-10 | 4 | Lyra Therapeutics, Inc. (LYRA) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, Perceptive LS (A), LLC, EDELMAN JOSEPH | Sale (S): 28,902 @ $5.18 · Sale (S): 3,247 @ $5.18 · Sale (S): 17,746 @ $4.75 · Sale (S): 1,993 @ $4.75 · Sale (S): 16,633 @ $4.54 · Sale (S): 1,869 @ $4.54 | EDGAR |
| 2025-10-22 | 4 | Adagio Medical Holdings, Inc. (ADGM) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Purchase (P): 1,344,999 (derivative) @ $0.18 · Purchase (P): 1,344,999 (derivative) @ $0.18 · Purchase (P): 1,344,999 (derivative) @ $0.18 · Purchase (P): 2,190,496 (derivative) @ $1.60 | EDGAR |
| 2025-08-05 | 4 | Orchestra BioMed Holdings, Inc. (OBIO) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Purchase (P): 700,000 @ $2.75 · Purchase (P): 1,500,000 (derivative) @ $2.75 | EDGAR |
| 2025-06-16 | 4 | MeiraGTx Holdings plc (MGTX) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Grant/award (A): 45,000 (derivative) @ $0 | EDGAR |
| 2025-06-13 | 4 | Solid Biosciences Inc. (SLDB) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Grant/award (A): 77,500 (derivative) @ $0 | EDGAR |
| 2025-05-01 | 4 | Acrivon Therapeutics, Inc. (ACRV) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Sale (S): 437,881 @ $1.41 · Sale (S): 298,886 @ $1.34 | EDGAR |
| 2025-04-29 | 4 | Acrivon Therapeutics, Inc. (ACRV) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Sale (S): 1,054,669 @ $1.95 · Sale (S): 215,283 @ $1.56 · Sale (S): 250,000 @ $1.41 | EDGAR |
| 2025-04-07 | 4 | Aldeyra Therapeutics, Inc. (ALDX) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Sale (S): 3,400,000 @ $1.42 | EDGAR |
| 2025-02-21 | 4 | Solid Biosciences Inc. (SLDB) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, Perceptive Xontogeny Venture Fund, LP, EDELMAN JOSEPH | Purchase (P): 5,000,000 @ $4.03 | EDGAR |
| 2025-02-14 | 4 | Adagio Medical Holdings, Inc. (ADGM) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH, C2 Life Sciences LLC | Grant/award (A): 64,167 | EDGAR |
| 2024-11-19 | 4 | Solid Biosciences Inc. (SLDB) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Grant/award (A): 34,400 (derivative) @ $0 | EDGAR |
| 2024-08-14 | 4 | MeiraGTx Holdings plc (MGTX) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Purchase (P): 1,250,000 @ $4 | EDGAR |
| 2024-06-17 | 4 | Nautilus Biotechnology, Inc. (NAUT) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Grant/award (A): 45,000 (derivative) @ $0 | EDGAR |
| 2024-06-07 | 4 | MeiraGTx Holdings plc (MGTX) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Grant/award (A): 45,000 (derivative) @ $0 | EDGAR |
| 2024-04-15 | 4 | Acrivon Therapeutics, Inc. (ACRV) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Purchase (P): 2,353,000 @ $8.50 | EDGAR |
| 2024-04-08 | 4 | Aldeyra Therapeutics, Inc. (ALDX) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Purchase (P): 140,281 @ $4.67 · Purchase (P): 37,712 @ $4.74 | EDGAR |
| 2024-04-03 | 4 | Aldeyra Therapeutics, Inc. (ALDX) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Purchase (P): 8,374 @ $3.25 · Purchase (P): 186,051 @ $3.44 · Purchase (P): 309,847 @ $4.09 | EDGAR |
| 2024-02-21 | 4 | Cerevel Therapeutics Holdings, Inc. (CERE) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Gift (G): 170,317 @ $0 | EDGAR |
| 2024-02-20 | 4 | LianBio (LIAN) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, EDELMAN JOSEPH | Option exercise (M): 36,300 @ $2.52 · Tax withholding (F): 19,218 @ $4.76 · Option exercise (M): 36,300 @ $2.52 · Tax withholding (F): 19,218 @ $4.76 · Option exercise (M): 36,300 (derivative) @ $0 · Option exercise (M): 36,300 (derivative) @ $0 | EDGAR |
| 2024-02-05 | 4 | Astria Therapeutics, Inc. (ATXS) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, Perceptive Xontogeny Venture Fund, LP, EDELMAN JOSEPH | Purchase (P): 2,481,350 @ $12.09 | EDGAR |
| 2024-01-12 | 4 | Solid Biosciences Inc. (SLDB) jointly with PERCEPTIVE LIFE SCIENCES MASTER FUND LTD, Perceptive Xontogeny Venture Fund, LP, EDELMAN JOSEPH | Purchase (P): 3,410,713 @ $5.53 | EDGAR |
FilingPulse's Form 4 archive currently extends back to 2024-01-11 and is expanding backward through EDGAR history — earlier filings by this insider may not be indexed yet. Names and roles are shown as filed.
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