FROST PHILLIP MD ET AL — SEC Form 4 filings

SEC reporting owner CIK 898860. 70 Form 4 filings on record with FilingPulse; latest filed 2026-09-14.

Transaction summary — filings shown

Covers the 50 most recent of 70 filings on record, filed 2024-09-27 to 2026-09-14. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.

By issuer — same filings

Open-market purchase/sale legs on non-derivative securities, grouped by issuer. Role is as filed on the newest filing for that issuer. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.

IssuerRole (as filed)FilingsPurchases (P)Sales (S)Other legs
OPKO HEALTH, INC. (OPK)CEO & Chairman, Director, 10% owner2548 legs · 5,497,709 sh · $7,839,2338
Cocrystal Pharma, Inc. (COCP)Director, 10% owner1211 legs · 314,000 sh · $300,2124
NOCOPI TECHNOLOGIES INC/MD/ (NNUP)10% owner41 leg · 195,852 sh · $215,4373
Fluent, Inc. (FLNT)10% owner922

Form 4 filings — FROST PHILLIP MD ET AL

FiledFormIssuerReported transactionsSource
2026-09-144NOCOPI TECHNOLOGIES INC/MD/ (NNUP)
jointly with Frost Gamma Investments Trust
Grant/award (A): 21,930 @ $0EDGAR
2026-08-064Cocrystal Pharma, Inc. (COCP)Purchase (P): 10,000 @ $0.98EDGAR
2026-08-054Cocrystal Pharma, Inc. (COCP)Purchase (P): 75,000 @ $0.94EDGAR
2026-02-254Cocrystal Pharma, Inc. (COCP)Purchase (P): 20,000 @ $1.00EDGAR
2026-02-094Cocrystal Pharma, Inc. (COCP)Purchase (P): 50,000 @ $0.95EDGAR
2026-01-134Cocrystal Pharma, Inc. (COCP)Grant/award (A): 24,615 (derivative) @ $0EDGAR
2026-01-024Cocrystal Pharma, Inc. (COCP)Purchase (P): 50,000 @ $0.95EDGAR
2025-12-314Cocrystal Pharma, Inc. (COCP)Purchase (P): 20,000 @ $0.97EDGAR
2025-12-294Cocrystal Pharma, Inc. (COCP)Purchase (P): 25,000 @ $0.97 · Purchase (P): 40,000 @ $0.97EDGAR
2025-11-284Cocrystal Pharma, Inc. (COCP)Purchase (P): 1,500 @ $1 · Purchase (P): 2,500 @ $0.99EDGAR
2025-11-254Cocrystal Pharma, Inc. (COCP)Purchase (P): 20,000 @ $0.94EDGAR
2025-11-214OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 102,371 @ $1.30 · Purchase (P): 3,894 @ $1.32 · Purchase (P): 89,375 @ $1.32 · Purchase (P): 191,490 @ $1.33 · Purchase (P): 192,870 @ $1.33EDGAR
2025-11-204OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 119,129 @ $1.32 · Purchase (P): 47,105 @ $1.32 · Purchase (P): 211,948 @ $1.33 · Purchase (P): 161,818 @ $1.33 · Purchase (P): 24,579 @ $1.34 · Purchase (P): 1,757 @ $1.34 · +1 moreEDGAR
2025-11-194OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 36,325 @ $1.28 · Purchase (P): 58,160 @ $1.28 · Purchase (P): 300 @ $1.29 · Purchase (P): 21,236 @ $1.29 · Purchase (P): 30,082 @ $1.30 · Purchase (P): 12,993 @ $1.30 · +3 moreEDGAR
2025-11-184OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 410 @ $1.25 · Purchase (P): 49,590 @ $1.25 · Purchase (P): 66,635 @ $1.25 · Grant/award (A): 46,700 @ $1.26 · Purchase (P): 15,000 @ $1.26 · Purchase (P): 1,772 @ $1.27 · +6 moreEDGAR
2025-10-314OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 150,000 @ $1.42EDGAR
2025-10-304Cocrystal Pharma, Inc. (COCP)Grant/award (A): 359,713 @ $1.39 · Grant/award (A): 719,426 (derivative) @ $1.39EDGAR
2025-09-154NOCOPI TECHNOLOGIES INC/MD/ (NNUP)
jointly with Frost Gamma Investments Trust
Grant/award (A): 21,930 @ $0EDGAR
2025-09-124/AFluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Other (J): 571,429 @ $0.00EDGAR
2025-09-084Fluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Other (J): 571,429 @ $0.00 · Disposition to issuer (D): 571,429 (derivative) @ $1.75EDGAR
2025-08-214Fluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Grant/award (A): 571,429 (derivative) @ $1.75 · Grant/award (A): 571,429 (derivative) @ $0EDGAR
2025-08-194OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Gift (G): 440,000 @ $0EDGAR
2025-08-084OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 675,000 @ $1.32EDGAR
2025-06-104NOCOPI TECHNOLOGIES INC/MD/ (NNUP)
jointly with Frost Gamma Investments Trust
Purchase (P): 195,852 @ $1.10EDGAR
2025-05-294OPKO HEALTH, INC. (OPK)Grant/award (A): 500,000 (derivative) @ $0EDGAR
2025-05-214Fluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Other (J): 909,297 @ $0.00 · Tax withholding (F): 212 @ $2.13 · Grant/award (A): 909,297 (derivative) @ $2.20 · Grant/award (A): 909,297 (derivative) @ $0 · Disposition to issuer (D): 909,297 (derivative) @ $2.20EDGAR
2025-04-104OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 125,000 @ $1.36EDGAR
2025-04-084OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 125,000 @ $1.48EDGAR
2025-04-014OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 100,000 @ $1.65EDGAR
2025-03-284OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 150,000 @ $1.70EDGAR
2025-03-274/AFluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Option exercise (M): 459,981 @ $0.00 · Tax withholding (F): 112 @ $2.04 · Grant/award (A): 459,981 (derivative) @ $2.17 · Option exercise (M): 459,981 (derivative) @ $2.17EDGAR
2025-03-214Fluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Option exercise (M): 459,981 @ $0.00 · Tax withholding (F): 112 @ $2.04 · Grant/award (A): 459,981 (derivative) @ $2.17 · Option exercise (M): 459,981 (derivative) @ $2.17EDGAR
2025-03-174OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 200,000 @ $1.74EDGAR
2025-03-044OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P) @ $436,500EDGAR
2025-03-034OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P) @ $1,703,250 · Purchase (P) @ $1,707,125EDGAR
2025-02-284OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 67,434 @ $1.71 · Purchase (P) @ $1,652,750EDGAR
2025-01-284OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 47,537 @ $1.47EDGAR
2024-12-134OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 125,000 @ $1.59EDGAR
2024-12-114OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 500,000 @ $1.56EDGAR
2024-12-114Fluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Option exercise/expiry (X): 647,892 @ $0.00 · Option exercise/expiry (X): 647,892 (derivative) @ $0EDGAR
2024-12-064/AFluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Grant/award (A): 647,892 (derivative) @ $2.31EDGAR
2024-12-044Fluent, Inc. (FLNT)
jointly with Frost Gamma Investments Trust
Purchase (P): 647,892 (derivative) @ $2.31EDGAR
2024-11-294OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 199,072 @ $1.53EDGAR
2024-11-224OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 100,000 @ $1.59EDGAR
2024-11-204/AOPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 280,183 @ $1.50EDGAR
2024-11-144OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 100,000 @ $1.62EDGAR
2024-11-084OPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P): 280,183 @ $1.50EDGAR
2024-10-114Cocrystal Pharma, Inc. (COCP)Grant/award (A): 27,100EDGAR
2024-10-094NOCOPI TECHNOLOGIES INC/MD/ (NNUP)
jointly with Frost Gamma Investments Trust
Grant/award (A): 21,930 @ $0EDGAR
2024-09-274/AOPKO HEALTH, INC. (OPK)
jointly with Frost Gamma Investments Trust
Purchase (P) @ $1,571,050EDGAR

FilingPulse's Form 4 archive currently extends back to 2024-01-10 and is expanding backward through EDGAR history — earlier filings by this insider may not be indexed yet. Names and roles are shown as filed.

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