OrbiMed Advisors Israel II Ltd — SEC Form 4 filings

SEC reporting owner CIK 1682093. 4 Form 4 filings on record with FilingPulse; latest filed 2026-04-09.

Transaction summary — filings shown

Covers all 4 filings on record, filed 2024-01-26 to 2026-04-09. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.

By issuer — same filings

Open-market purchase/sale legs on non-derivative securities, grouped by issuer. Role is as filed on the newest filing for that issuer. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.

IssuerRole (as filed)FilingsPurchases (P)Sales (S)Other legs
Upstream Bio, Inc. (UPB)Director, 10% owner12 legs · 825,000 sh · $14,025,0006
Adicet Bio, Inc. (ACET)10% owner35 legs · 8,125,000 sh · $12,500,0004 legs · 104,658 sh · $674,847

Form 4 filings — OrbiMed Advisors Israel II Ltd

FiledFormIssuerReported transactionsSource
2026-04-094Adicet Bio, Inc. (ACET)
jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP V LLC, OrbiMed Capital GP VI LLC, OrbiMed Genesis GP LLC, OrbiMed Israel GP II, L.P., OrbiMed Israel GP Ltd., OrbiMed Israel BioFund GP Limited Partnership
Sale (S): 29,319 @ $6.53 · Sale (S): 2,400 @ $6.38 · Sale (S): 32,523 @ $6.29 · Sale (S): 40,416 @ $6.52EDGAR
2025-10-104Adicet Bio, Inc. (ACET)
jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP V LLC, OrbiMed Capital GP VI LLC, OrbiMed Genesis GP LLC, OrbiMed Israel GP II, L.P., OrbiMed Israel GP Ltd., OrbiMed Israel BioFund GP Limited Partnership
Purchase (P): 1,500,000 @ $1 · Purchase (P): 3,500,000 @ $1EDGAR
2024-10-174Upstream Bio, Inc. (UPB)
jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP VIII LLC, OrbiMed Israel GP II, L.P.
Conversion (C): 721,956 · Purchase (P): 165,000 @ $17 · Conversion (C): 2,887,833 · Purchase (P): 660,000 @ $17 · Conversion (C): 524,500 (derivative) · Conversion (C): 2,098,000 (derivative) · +2 moreEDGAR
2024-01-264Adicet Bio, Inc. (ACET)
jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP V LLC, OrbiMed Capital GP VI LLC, OrbiMed Genesis GP LLC, OrbiMed Israel GP II, L.P., OrbiMed Israel GP Ltd., OrbiMed Israel BioFund GP Limited Partnership
Purchase (P): 1,841,100 @ $2.40 · Purchase (P): 242,200 @ $2.40 · Purchase (P): 1,041,700 @ $2.40EDGAR

FilingPulse's Form 4 archive currently extends back to 2024-01-11 and is expanding backward through EDGAR history — earlier filings by this insider may not be indexed yet. Names and roles are shown as filed.

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