OrbiMed Capital GP VI LLC — SEC Form 4 filings
SEC reporting owner CIK 1682115. 25 Form 4 filings on record with FilingPulse; latest filed 2026-04-23.
Transaction summary — filings shown
Covers all 25 filings on record, filed 2024-01-16 to 2026-04-23. Counts and totals are arithmetic on values as filed — descriptive data, not a recommendation.
- Open-market purchases (code P, non-derivative): 15 legs across 7 filings — 12,474,965 shares, $45,000,018 total (shares × price as filed).
- Open-market sales (code S, non-derivative): 51 legs across 13 filings — 5,764,782 shares, $50,324,603 total (shares × price as filed).
- Other reported legs (grants, option exercises, tax withholding, gifts, derivative-security transactions, …): 8.
- Largest priced transaction: purchase of 1,689,189 shares @ $4.44 ($7,499,999) in Prelude Therapeutics Inc, filed 2026-04-23.
By issuer — same filings
Open-market purchase/sale legs on non-derivative securities, grouped by issuer. Role is as filed on the newest filing for that issuer. Dollar totals cover priced legs only (shares × price as filed). Ordered by priced transaction value, largest first.
| Issuer | Role (as filed) | Filings | Purchases (P) | Sales (S) | Other legs |
|---|---|---|---|---|---|
| Disc Medicine, Inc. (IRON) | Director | 4 | 3 legs · 83,334 sh · $3,000,024 | 27 legs · 370,551 sh · $20,108,066 | — |
| Edgewise Therapeutics, Inc. (EWTX) | Director, 10% owner | 2 | 3 legs · 951,316 sh · $14,999,995 | — | — |
| Adicet Bio, Inc. (ACET) | 10% owner | 3 | 5 legs · 8,125,000 sh · $12,500,000 | 4 legs · 104,658 sh · $674,847 | — |
| ARS Pharmaceuticals, Inc. (SPRY) | Director | 2 | — | 5 legs · 952,377 sh · $12,585,998 | — |
| Prelude Therapeutics Inc (PRLD) | Director, 10% owner | 1 | 2 legs · 2,815,315 sh · $12,499,999 | — | — |
| NeuroPace Inc (NPCE) | 10% owner | 6 | — | 14 legs · 765,768 sh · $11,277,121 | — |
| Compass Therapeutics, Inc. (CMPX) | Director, 10% owner | 1 | — | 1 leg · 3,571,428 sh · $5,678,571 | — |
| scPharmaceuticals Inc. (SCPH) | 10% owner | 1 | 2 legs · 500,000 sh · $2,000,000 | — | — |
| ALPINE IMMUNE SCIENCES, INC. (ALPN) | Director | 2 | — | — | 4 |
| ImageneBio, Inc. (IMA) | Director | 2 | — | — | 3 |
+1 more issuer among the filings shown — every filing appears in the table below.
Form 4 filings — OrbiMed Capital GP VI LLC
| Filed | Form | Issuer | Reported transactions | Source |
|---|---|---|---|---|
| 2026-04-23 | 4 | Prelude Therapeutics Inc (PRLD) jointly with ORBIMED ADVISORS LLC, ORBIMED CAPITAL LLC, OrbiMed Genesis GP LLC | Purchase (P): 1,689,189 @ $4.44 · Purchase (P): 1,126,126 @ $4.44 | EDGAR |
| 2026-04-16 | 4 | ImageneBio, Inc. (IMA) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Purchase (P): 336,603 (derivative) · Purchase (P): 384,689 (derivative) | EDGAR |
| 2026-04-09 | 4 | Adicet Bio, Inc. (ACET) jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP V LLC, OrbiMed Genesis GP LLC, OrbiMed Advisors Israel II Ltd, OrbiMed Israel GP II, L.P., OrbiMed Israel GP Ltd., OrbiMed Israel BioFund GP Limited Partnership | Sale (S): 29,319 @ $6.53 · Sale (S): 2,400 @ $6.38 · Sale (S): 32,523 @ $6.29 · Sale (S): 40,416 @ $6.52 | EDGAR |
| 2025-10-10 | 4 | Adicet Bio, Inc. (ACET) jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP V LLC, OrbiMed Genesis GP LLC, OrbiMed Advisors Israel II Ltd, OrbiMed Israel GP II, L.P., OrbiMed Israel GP Ltd., OrbiMed Israel BioFund GP Limited Partnership | Purchase (P): 1,500,000 @ $1 · Purchase (P): 3,500,000 @ $1 | EDGAR |
| 2025-08-12 | 4 | Turnstone Biologics Corp. (TSBX) jointly with ORBIMED ADVISORS LLC | Code (U): 3,099,265 | EDGAR |
| 2025-07-30 | 4 | ImageneBio, Inc. (IKNA) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Grant/award (A): 83,611 @ $2.49 | EDGAR |
| 2025-05-16 | 4 | NeuroPace Inc (NPCE) jointly with ORBIMED ADVISORS LLC | Sale (S): 134,136 @ $15.83 · Sale (S): 34,000 @ $15.94 | EDGAR |
| 2025-04-11 | 4 | Compass Therapeutics, Inc. (CMPX) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Sale (S): 3,571,428 @ $1.59 | EDGAR |
| 2025-04-04 | 4 | Edgewise Therapeutics, Inc. (EWTX) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Purchase (P): 372,578 @ $20.13 · Purchase (P): 124,193 @ $20.13 | EDGAR |
| 2025-03-26 | 4 | Disc Medicine, Inc. (IRON) jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP VIII LLC, OrbiMed Genesis GP LLC | Sale (S): 1,956 @ $54.11 · Sale (S): 3,026 @ $54.11 · Sale (S): 756 @ $54.11 | EDGAR |
| 2025-03-21 | 4 | Disc Medicine, Inc. (IRON) jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP VIII LLC, OrbiMed Genesis GP LLC | Sale (S): 13,517 @ $54.02 · Sale (S): 20,911 @ $54.02 · Sale (S): 5,228 @ $54.02 · Sale (S): 941 @ $54.01 · Sale (S): 1,457 @ $54.01 · Sale (S): 364 @ $54.01 · +3 more | EDGAR |
| 2025-03-12 | 4 | Disc Medicine, Inc. (IRON) jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP VIII LLC, OrbiMed Genesis GP LLC | Sale (S): 68,766 @ $54.29 · Sale (S): 106,384 @ $54.29 · Sale (S): 26,596 @ $54.29 · Sale (S): 136 @ $55.01 · Sale (S): 211 @ $55.01 · Sale (S): 53 @ $55.01 · +9 more | EDGAR |
| 2024-08-28 | 4 | ARS Pharmaceuticals, Inc. (SPRY) jointly with ORBIMED ADVISORS LLC, ORBIMED CAPITAL LLC | Sale (S): 83,695 @ $13 | EDGAR |
| 2024-08-23 | 4 | ARS Pharmaceuticals, Inc. (SPRY) jointly with ORBIMED ADVISORS LLC, ORBIMED CAPITAL LLC | Sale (S): 394,400 @ $13.52 · Sale (S): 13,300 @ $14.61 · Sale (S): 391,482 @ $12.94 · Sale (S): 69,500 @ $13.03 | EDGAR |
| 2024-08-15 | 4 | scPharmaceuticals Inc. (SCPH) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Purchase (P): 478,342 @ $4 · Purchase (P): 21,658 @ $4 | EDGAR |
| 2024-06-20 | 4 | Disc Medicine, Inc. (IRON) jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP VIII LLC, OrbiMed Genesis GP LLC | Purchase (P): 28,404 @ $36 · Purchase (P): 43,944 @ $36 · Purchase (P): 10,986 @ $36 | EDGAR |
| 2024-05-20 | 4 | ALPINE IMMUNE SCIENCES, INC. (ALPN) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Code (U): 2,416,181 · Code (U): 264,315 | EDGAR |
| 2024-05-03 | 4 | NeuroPace Inc (NPCE) jointly with ORBIMED ADVISORS LLC | Sale (S): 15,690 @ $14.02 · Sale (S): 8,842 @ $14.01 · Sale (S): 4,674 @ $14.03 | EDGAR |
| 2024-04-26 | 4 | NeuroPace Inc (NPCE) jointly with ORBIMED ADVISORS LLC | Sale (S): 1,781 @ $14.06 | EDGAR |
| 2024-04-23 | 4 | NeuroPace Inc (NPCE) jointly with ORBIMED ADVISORS LLC | Sale (S): 18,253 @ $14.02 · Sale (S): 24,609 @ $14.05 · Sale (S): 21,791 @ $14.29 | EDGAR |
| 2024-04-18 | 4 | NeuroPace Inc (NPCE) jointly with ORBIMED ADVISORS LLC | Sale (S): 14,069 @ $14.01 · Sale (S): 300 @ $14.15 · Sale (S): 2,623 @ $14.06 | EDGAR |
| 2024-04-15 | 4 | NeuroPace Inc (NPCE) jointly with ORBIMED ADVISORS LLC | Sale (S): 461,899 @ $14.49 · Sale (S): 23,101 @ $14.42 | EDGAR |
| 2024-01-26 | 4 | Adicet Bio, Inc. (ACET) jointly with ORBIMED ADVISORS LLC, OrbiMed Capital GP V LLC, OrbiMed Genesis GP LLC, OrbiMed Advisors Israel II Ltd, OrbiMed Israel GP II, L.P., OrbiMed Israel GP Ltd., OrbiMed Israel BioFund GP Limited Partnership | Purchase (P): 1,841,100 @ $2.40 · Purchase (P): 242,200 @ $2.40 · Purchase (P): 1,041,700 @ $2.40 | EDGAR |
| 2024-01-25 | 4 | Edgewise Therapeutics, Inc. (EWTX) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Purchase (P): 454,545 @ $11 | EDGAR |
| 2024-01-16 | 4 | ALPINE IMMUNE SCIENCES, INC. (ALPN) jointly with ORBIMED ADVISORS LLC, OrbiMed Genesis GP LLC | Option exercise/expiry (X): 145,251 @ $12.74 · Option exercise/expiry (X): 145,251 (derivative) @ $0 | EDGAR |
FilingPulse's Form 4 archive currently extends back to 2024-01-11 and is expanding backward through EDGAR history — earlier filings by this insider may not be indexed yet. Names and roles are shown as filed.
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